Some features of severe falciparum malaria

CNS
Cerebral malaria (coma convulsion)
Renal
Haemoglobinuria (blackwater fever)
Oliguria
Uraemia (acute tubular necrosis)
Blood
Severe anaemia (haemolysis and dyserythropoiesis)
Disseminated intravascular coagulation (DIC)
Respiratory
Acute respiratory distress syndrome
Metabolic
Hypoglycaemia (particularly in children)
Metabolic acidosis
Gastrointestinal/liver
Diarrhoea
Jaundice
Splenic rupture
Other
Shock - hypotensive
Hyperpyrexia